Lipid dynamics and lipid-protein interactions in rat hepatocyte plasma membranes.
نویسندگان
چکیده
منابع مشابه
Lipid-protein interactions in membranes.
The interactions of lipids with integral and peripheral proteins can be studied in reconstituted and natural membranes using spin label electron spin resonance (ESR) spectroscopy. The ESR spectra reveal a reduction in mobility of the spin-labelled lipid species, and in certain cases evidence is obtained for a partial penetration of the peripheral proteins into the membrane. The latter may be re...
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OmpG is an intermediate size, monomeric, outer membrane protein from Escherichia coli, with n beta = 14 beta-strands. It has a large pore that is amenable to modification by protein engineering. The stoichiometry ( N b = 20) and selectivity ( K r = 0.7-1.2) of lipid-protein interaction with OmpG incorporated in dimyristoyl phosphatidylcholine bilayer membranes was determined with various 14-pos...
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Sterols are main constituents of many membranes. Cholesterol is the most abundant sterol in membranes of higher organisms. Many studies have been undertaken to try to understand the function of cholesterol, in which the interaction between cholesterol and various phosphatidylcholines were investigated in monolayers and liposomes (Phillips, 1972). The physicochemical state of the lipids determin...
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A membrane state transition has been reported to occur in erythrocyte ghosts in the region of 20°C [ 1,2] which has been tentatively identified as a gel-liquid crystalline phase transition of some portion of the membrane lipids. Such a phase transition would be surprising as the high cholesterol content of the erythrocyte membrane would be expected to eliminate phase transition phenomena if the...
متن کاملTheoretical study of protein--lipid interactions in bilayer membranes.
An analysis is given for the perturbation of the order and composition of lipid bilayers near an intrinsic membrane protein. Two cases are examined: the protein influences the lipid order (i.e., "fluidity"), and the protein associates with one component of a lipid mixture preferentially. The order perturbation is studied as a function of temperature and lateral pressure by using Landau--de Genn...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1980
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)70392-5